Clobetasol propionate, Neomycin, Nystatin
THE DESCRIPTION :
Clobetasol propionate is a highly active corticosteroid with topical anti-inflammatory activity. The major effect of clobetasol propionate on the skin is a non-specific anti-inflammatory response, due in part to vasoconstriction and decreased collagen synthesis. The use of nystatin in the local treatment of candidal skin infections and neomycin as a broad spectrum antibiotic is well known. The main action of the preparation is based on the anti-inflammatory activity of the corticosteroid. Antibacterial activity and broad-spectrum anti-candida provided by the combination of neomycin and nystatin allows this effect to be used in the treatment of conditions infected or likely to be so.
Neotincol cream is indicated in more resistant dermatoses such as recalcitrant eczema and psoriasis (excluding psoriasis generalized plaque) where a bacterial infection or secondary candidiasis is present, suspected or likely to occur, such as when using occlusive dressings.
Neotincol cream is contraindicated in rosacea, acne vulgaris and perioral dermatitis, primary skin viral infections (eg, herpes simplex, chickenpox) and hypersensitivity to the preparation. A possibility of increased absorption exists in very young children, so it is not recommended to be used in newborns and infants (less than 2 years old).
Long-term continuous topical treatment should be avoided whenever possible, especially in infants and children. because adrenal suppression can occur easily even without occlusion if applied to the eyelids, eye care is required, as glaucoma could result. If the cream gets into the eye, the affected eye should be washed thoroughly with a large amount of water.